Exaggerated placental site erroneously diagnosed as non-metastatic trophoblastic disease. A case report

Background: Exaggerated placental site (EPS) is classified as a non-neoplas tic trophoblastic lesion, and histologically it consists of endometrial and myometrial invasion of intermediate trophoblasts and syncytiotrophoblasts and it differs morphologically from placental site trophoblastic tumors and placental nodules. The purpose of this report is to increase physicians' a wareness of this lesion. Case: A 48-year-old woman with post-molar rising sshCG titers and a clinica l diagnosis of non-metastatic trophoblastic disease underwent hysterectomy. Final histopathology showed exaggerated placental site - a lesion often un familiar to clinicians. Conclusion: It is suggested that operative hysteroscopy may be useful in th e diagnosis and management of EPS.