A. Gurlek et al., Frequency of severe hypoglycaemia in type 1 and type 2 diabetes during conventional insulin therapy, EXP CL E D, 107(3), 1999, pp. 220-224
Citations number
19
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
To determine the frequency of severe hypoglycaemia during conventional insu
lin therapy in juvenile-onset and adult-onset type 1 and in type 2 diabetes
mellitus (DM), we retrospectively analysed the medical records of 165 Turk
ish diabetic patients who have been treated with conventional insulin. Pati
ents were divided into 3 subgroups with respect to the type of diabetes: 33
had juvenile-onset Type 1 DM, 18 had adult-onset type 1 DM, and 114 had ty
pe 2 DM. The diabetic subgroups were found to be comparable with regard to
mean frequency of severe hypoglycaemia (juvenile-onset type 1 DM: 0.20 epis
ode . patient(-1) . year-1, adult-onset type 1 DM: 0.10 episode. patient(-1
) . year(-1) type 2 DM: 0.15 episode . patient(-1) . year(-1)). Frequency o
f severe hypoglycaemia necessitating in-hospital treatment was 0.05 episode
. patient(-1) . year(-1) for all diabetic subgroups. The data clearly indi
cate that the extent of the problem of severe hypoglycaemia during conventi
onal insulin therapy in type 2 DM is comparable with both juvenile and adul
t-onset forms of type 1 DM in Turkish diabetic population.