Synthesis and antibacterial activity of 2-aryl-2, 5-dibydro-3(3H)-oxo-pyridazino[4,3-b]indole-4-carboxylic acids

Authors
Palluotto, F Carotti, A Casini, G Ferappi, M Rosato, A Vitali, C Campagna, F
Citation
F. Palluotto et al., Synthesis and antibacterial activity of 2-aryl-2, 5-dibydro-3(3H)-oxo-pyridazino[4,3-b]indole-4-carboxylic acids, FARMACO, 54(3), 1999, pp. 191-194
Citations number
8
Categorie Soggetti
Pharmacology & Toxicology
Journal title
FARMACO
ISSN journal
0014827X → ACNP
Volume
54
Issue
3
Year of publication
1999
Pages
191 - 194
Database
ISI
SICI code
0014-827X(19990331)54:3<191:SAAAO2>2.0.ZU;2-A
Abstract
The in vitro antibacterial and antifungal activities of a series of pyridaz inoindolonic acids II against some selected representative of Gram-positive , Gram-negative bacteria and fungi have been investigated. Some interesting observations among the structural features necessary for high antibacteria l activity are presented and discussed. (C) 1999 Elsevier Science S.A. All rights reserved.