A one-step transformation of (S)-1-benzoyl-3-[(E)-dimethylaminomethylidene]-5-methoxycarbonyl-pyrrolidin-2-one into quinolizinyl- and 2H-2-pyranonyl-substituted alanine derivatives

Authors
Skof, M Svete, J Stanovnik, B
Citation
M. Skof et al., A one-step transformation of (S)-1-benzoyl-3-[(E)-dimethylaminomethylidene]-5-methoxycarbonyl-pyrrolidin-2-one into quinolizinyl- and 2H-2-pyranonyl-substituted alanine derivatives, HETEROCYCLE, 51(5), 1999, pp. 1051-1058
Citations number
21
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
51
Issue
5
Year of publication
1999
Pages
1051 - 1058
Database
ISI
SICI code
0385-5414(19990501)51:5<1051:AOTO(>2.0.ZU;2-R
Abstract
(S)-1-Benzoyl-3-[(E)-dimethylaminomethylidene]-5-methoxycarbonylpyrrolidin- 2-one (1) was transformed in one step with various 1,3-dinucleophiles (2-14 ) into the corresponding N-benzoyl-3-quinolizinyl- (15-18) and N-benzoyl-3- (2H-2-pyranonyl)alanine methyl esters (19-27).