Pancreas divisum

Citation
S. Varshney et Cd. Johnson, Pancreas divisum, INT J PANCR, 25(2), 1999, pp. 135-141
Citations number
58
Categorie Soggetti
da verificare
Journal title
INTERNATIONAL JOURNAL OF PANCREATOLOGY
ISSN journal
01694197 → ACNP
Volume
25
Issue
2
Year of publication
1999
Pages
135 - 141
Database
ISI
SICI code
0169-4197(199904)25:2<135:PD>2.0.ZU;2-#
Abstract
Endoscopic retrograde cholangiopancreatography (ERCP) is diagnostic. Simila rly, secretin stimulated ultrasonography may positively predict the outcome of minor papilla therapy. Computed tomography is only helpful for the dete ction of complications. Magnetic resonance cholangiopancreatography (MRCP) is a new noninvasive diagnostic tool in development. It is accurate and mig ht replace ERCP for diagnosis. Clinically, symptomatic patients with PD may be divided into five groups: g roup 1, those with minimal symptoms; group 2, those with recurrent acute pa ncreatitis or upper abdominal pain with no other cause; group 3, those with chronic pancreatitis; group 4, those with chronic pancreatic pain; and gro up 5, those with other complications. Group 1 should be treated with medical therapy alone. The response to surgi cal or endoscopic therapy of the minor papilla is good in group 2 (75-90%), moderate in group 3 (40-60%), and poor in group 4 (20-40%). A few patients require other forms of pancreatic surgery, such as Puestow's operation, Be ger's operation, or distal pancreatectomy. With careful selection of patien t and therapy, good response to the therapy can be achieved. Pancreas divisum (PD) is the most common congenital anomaly of the pancreas , with an incidence of up to 10%. Symptoms or complications developing in i ndividuals with PD are uncommon (5% of individuals with PD). It seems unlik ely that PD alone could cause obstructive pancreatitis and the presence of another factor, such as minor papilla insufficiency, is probably required f or this relatively common anomaly to develop complications.