Purpose: The purpose of this study was to assess the psychosocial effects o
f growing up with a nd living with amblyopia and to determine whether patie
nts with amblyopia but without strabismus encounter psychosocial problems s
imilar to those encountered by individuals with strabismus. Methods: A 20-q
uestion survey focusing on medical background, education, self-image, histo
ry of amblyopia, treatment of amblyopia, and effects of amblyopia on work,
school, friendships, and self-esteem was provided to patients with amblyopi
a but not strabismus at Saint Louis University Eye Institute and at the Uni
versity of Iowa Department of Ophthalmology. In addition, patients were eva
luated in terms of somatization, obsession-compulsion, interperson al sensi
tivity, depression, a nd anxiety. Results for patients with amblyopia were
compared with those of strabismic, normative, and psychopathologic groups u
sing the Hopkins Symptom Checklist (HSC). Results: Twenty-five patients wit
h amblyopia but without strabismus or previous surgery responded. A signifi
cant number of patients felt th at amblyopia interfered with school (52%) a
nd work (48%) to some degree and were generally affected in their lifestyl
e (50%). Fewer were affected in their play of sports (40%) or were influenc
ed as to their job choice (36%). Patients with amblyopia as a whole had a g
reater degree of somatization, obsessive-compulsive behavior, interpersonal
sensitivity, depression, and anxiety than patients with strabismus and HSC
control subjects. Differences between patients with amblyopia a nd those w
ith strabismus we re not statistically significant (P>.05), but differences
between patients with amblyopia and HSC control subjects were significant
(P<.05) in each category. Patients with amblyopia, however, were less sympt
omatic in these areas than HSC Anxious and HSC Depressed groups. Conclusion
: Psychosocial difficulties related to amblyopia affect individuals' self-i
mage, work, school, and friendships. Amblyopia has a significant effect on
psychosocial functioning and warrants aggressive screening, prevention and
treatment during the amblyogenic years.