Intramural ileocaecocolic leiomyosarcoma is described in an elderly neutere
d male domestic shorthaired cat with poor appetite and weight loss. Histolo
gical examination of the resected lesion revealed a poorly differentiated s
oft tissue sarcoma and a diagnosis of leiomyosarcoma was confirmed by posit
ive Immunohistochemical staining for vimentin and a-smooth muscle actin. Po
stoperative survival time was 102 days before local recurrence justified eu
thanasia.