Preparation and fungitoxicity of some dichloro-8-quinolinols

2,5-, 3,5-, 3,7-, 4,5-, 5,6-, und 6,7-Dichloro-8-quinolinols were prepared and tested along with their 3,6- and 5,7-analogues against six fungi (Asper gillus niger; A. oryzae, Myrothecium verrucaria, Trichoderma viride, Mucor cirinelloides, and Trichophyton mentagrophytes) in Sabouraud dextrose broth . Most of the compounds were strongly antifungal, inhibiting five of the Fu ngi below 1 mu g/ml. This activity is attributed to intramolecular synergis m. M. cirinelloides was inhibited less by these compounds.