Jw. Barrington et P. Bowensimpkins, THE LEVONORGESTREL INTRAUTERINE SYSTEM IN THE MANAGEMENT OF MENORRHAGIA, British journal of obstetrics and gynaecology, 104(5), 1997, pp. 614-616
Objective To assess the effect of a levonorgestrel releasing intrauter
ine system in the management of menorrhagia. Design A prospective stud
y. Setting A district general hospital in South Wales. Methods Fifty w
omen with a failed trial of medical therapy and awaiting hysterectomy
or transcervical resection of the endometrium (TCRE) were treated with
a levonorgestrel intrauterine system. The menstrual loss was estimate
d using a modified pictorial chart together with a full blood count an
d ferritin measurement preinsertion and at three and six to nine month
s postinsertion. Results The menstrual loss was reduced to acceptable
levels in 37 women at three months and a further four by six to nine m
onths. In all, 41 patients were taken off the waiting list for surgery
, four of whom became amenorrhoeic. There was no significant change in
full blood count nor ferritin measurement despite unscheduled bleedin
g for six to eight weeks postinsertion. Fifty-six percent of patients
noticed considerable improvement or cure of their premenstrual syndrom
e symptoms; 80% noted a reduction in dysmenorrhoea. Conclusion The lev
onorgestrel releasing intrauterine system is an effective nonsurgical
treatment for the management of menorrhagia and dysmenorrhoea that has
additional benefit as a contraceptive and in relieving premenstrual s
yndrome.