Thrombospondins, tumor angiogenesis, and breast cancer.

Authors
Clezardin, P Bruno-Bossio, G Fontana, A Serre, CM Magnetto, S Frappart, L
Citation
P. Clezardin et al., Thrombospondins, tumor angiogenesis, and breast cancer., PATH BIOL, 47(4), 1999, pp. 368-374
Citations number
39
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
PATHOLOGIE BIOLOGIE
ISSN journal
03698114 → ACNP
Volume
47
Issue
4
Year of publication
1999
Pages
368 - 374
Database
ISI
SICI code
0369-8114(199904)47:4<368:TTAABC>2.0.ZU;2-U
Abstract
Thrombospondin-1 and -2 are extracellular matrix proteins that are overexpr essed in breast cancer tissue, Their role in breast cancer remains unknown. This article reviews the potential effects of thrombospondin-l and -2 in b reast cancer tumori genesis and metastatic dissemination.