Visceral leishmaniasis associated with Wegener's disease: utilization of lipid complex amphetericin B and liposomal amphetericin B

BACKGROUND: Leishmaniasis in a patient with Wegeneris disease raises the pr oblem of amphotericin toxicity further compromizing the pre-existing renal disorder. CASE REPORT: An anemic patient treated for Wegeneris disease developed visc eral leishmaniasis. This renal failure patient was treated with lipid compl ex amphetericin B and liposomal amphetericin B. We report outcome at 10 mon ths follow-up. DISCUSSION: The new formulations of amphetericin B allow effective treatmen t of visceral leishmaniasis in renal failure patients. Long-lasting results are probably favored by the interruption of immuno-suppressive therapy.