Fractal-like networks effectively endow Life with an additional fourth spat
ial dimension. This is the origin of quarter-power scaling that is so perva
sive in biology, Organisms have evolved hierarchical branching networks tha
t terminate in size-invariant units, such as capillaries, Leaves, mitochond
ria, and oxidase molecules. Natural selection has tended to maximize both m
etabolic capacity, by maximizing the scaling of exchange surface areas, and
internal efficiency, by minimizing the scaling of transport distances and
times. These design principles are independent of detailed dynamics and exp
licit models and should apply to virtually all organisms.