Versatility of Weinreb amides in the Knorr pyrrole synthesis

Authors
Alberola, A Ortega, AG Sadaba, ML Sanudo, C
Citation
A. Alberola et al., Versatility of Weinreb amides in the Knorr pyrrole synthesis, TETRAHEDRON, 55(21), 1999, pp. 6555-6566
Citations number
27
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
21
Year of publication
1999
Pages
6555 - 6566
Database
ISI
SICI code
0040-4020(19990521)55:21<6555:VOWAIT>2.0.ZU;2-Q
Abstract
N-Methoxy-N-methyl-alpha-enaminocarboxamides were prepared starting from en amines and Weinreb alpha-aminoamides. Their reaction with oganometallic com pounds and subsequent cyclization constitute a versatile alternative in the Knorr pyrrole synthesis. (C) 1999 Elsevier Science Ltd. All rights reserve d.