Synthesis of haptens for the development of a solid-phase immobilized epitope-immunoassay (SPIE-IA) of AZT-TP

Authors
Lebeau, L Brossette, T Goujon, L Creminon, C Grassi, J Mioskowski, C
Citation
L. Lebeau et al., Synthesis of haptens for the development of a solid-phase immobilized epitope-immunoassay (SPIE-IA) of AZT-TP, TETRAHEDR L, 40(23), 1999, pp. 4323-4326
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
23
Year of publication
1999
Pages
4323 - 4326
Database
ISI
SICI code
0040-4039(19990604)40:23<4323:SOHFTD>2.0.ZU;2-S
Abstract
The synthesis of the reduced form of AZT-triphosphate, 3'-amino-3'-deoxythy midine-5'-triphosphate, and of its stable analog, 3'-amino-3'-deoxythymidin e-5'-(alpha;beta:beta,gamma-bis-methylene)triphosphate, is described. AMT-T P and AMT-PCPCP were prepared to develop a specific immunometric assay for AZT-TP. (C) 1999 Elsevier Science Ltd. All rights reserved.