Stereoselective addition of phenyl selenyl chloride to methoxy alkenes derived from N-protected chiral alpha-amino acids.

Authors
Demarcus, M Filigheddu, SN Mann, A Taddei, M
Citation
M. Demarcus et al., Stereoselective addition of phenyl selenyl chloride to methoxy alkenes derived from N-protected chiral alpha-amino acids., TETRAHEDR L, 40(23), 1999, pp. 4417-4420
Citations number
7
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
23
Year of publication
1999
Pages
4417 - 4420
Database
ISI
SICI code
0040-4039(19990604)40:23<4417:SAOPSC>2.0.ZU;2-Z
Abstract
(E)-Methoxy alkenes derived from N-Boc or NCbz alpha-amino acids undergo st ereoselective addition of phenyl selenyl chloride in the presence of Ti(Oi- Pr)(4) and LiCl to give the corresponding phenylselenyl aldehydes that can be easily transformed into new enantiomericalIy pure amino acids containing an aziridine ring. (C) 1999 Elsevier Science Ltd. All rights reserved.