Antimicrobial activity studies of mononuclear and binuclear mixed-ligand copper(II) complexes derived from Schiff base ligands and 1,10-phenanthroline

Mixed-ligand complexes of copper(II) with 1,10-phenanthroline and various S chiff bases have been prepared and characterized by elemental analysis, ele ctronic and i.r. spectra, magnetic moment and molar conductance data. The S chiff base behave as bidentate ligands, and the mixed-ligand copper(II) com plexes of the ligands HL1", HL2" and HL4" are binuclear. The conductivity d ata for all the complexes are consistent with those expected for an electro lyte. Antimicrobial activities of some of the ligands and complexes have be en tested against Bacillus megaterium and Candida tropicalis. H-1 and C-13 n.m.r. spectra have been recorded in order to solve the solution structure of the ligands. Thermal properties of all complexes have been studied by th e d.t.a. and t.g.a. techniques.