HIV-associated eosinophilic folliculitis in an infant

HIV-associated eosinophilic folliculitis (HIV-EF), which is a well-known en tity in adults, has not been described in children. Although Ofuji's diseas e (OD) or eosinophilic pustular folliculitis (EPF) has been described in ch ildren and shares histopathologic features with HIV-EF, it is a distinct en tity with characteristic clinical features. We report the occurrence of eos inophilic folliculitis in an 8-month-old HIV-positive patient and discuss t he clinical, pathologic and possible pathogenetic aspects thereof. Ln addit ion, differences in the clinical manifestations of the present case and tha t of I-EPF are addressed. Because of clinicopathologic similarities between the present case and HIV-associated eosinophilic folliculitis (HIV-EF) in adults, we believe that eosinophilic folliculitis in this patient represent s a cutaneous manifestation of HIV infection, rather than co-incidental occ urrence of the infantile form of Ofuji's disease in an HIV-positive patient .