Stress leak point pressures and urethral pressure profile tests in clinically normal female dogs

Objective-To develop a stress leak point pressure (IPP) lest for dogs, dete rmine IPP for continent female dogs, and determine urethral pressure profil e (UPP) values for nonanesthetized, continent female dogs. Animals-22 continent female dogs weighing from 21 to 29 kg. Procedure-A standard UPP test and a modification of the LPP test used in wo men were performed on all dogs. On 3 occasions, dogs underwent UPP testing while awake. They then were anesthetized with propofol, and LPP was measure d at bladder volumes of 75, 100, and 150 mi. For LPP tests, abdominal press ure was applied by inflating a human blood pressure cuff placed around the dog's abdomen. LPP were recorded through a urethral catheter (bladder LPP) and a rectal balloon catheter (abdominal LPP), Results-Mean +/- SD and median maximal urethral closure pressure was 110.1 +/- 20.2 and 109.0 cm water, respectively. Mean bladder LPP for the 75, 100 , and 150 mi bladder volumes was 172.4 cm water. Significant differences am ong LPP for the 3 bladder volumes were not detected. Conclusions-Stress IPP can be recorded in female dogs.