Patient-controlled sedation with propofol for extracorporeal shock wave lithotripsy.

Objective: Evaluation of patient-controlled sedation with propofol for extr acorporeal shock wave lithotripsy (ESWL) using an EDAP(TM) LT01 lithotripto r. Study design: Prospective clinical study. Patients: Fifty consecutive patients, ASA I or II, aged 18-65 years. Methods: Patients received 50 mg of propofol five minutes before ESWL, then they self-administered 50 mg bolus doses of propofol with a ten minutes lo ckout interval. Pain (1-100 mm VAS) and sedation (four points scale) were a ssessed every five minutes. Patient satisfaction was recorded at the end of the procedure, Pharmacokinetic simulation was done with the Marsh's data s et. Results: Three patients were excluded. Patients received a mean propofol do se of 147 +/- 68 mg during the procedure with a mean duration of 47 +/- 8 m inutes. The median of the higher sedation scores was 2 (drowsy) and mean ma ximal VAS was 40 +/- 20 mm (10-70). No complications were recorded. Thirty- nine patients (83%) were satisfied or very satisfied by patient-controlled sedation. Conclusion: Patient-controlled sedation with propofol is a safe and efficie nt mode of administration of an hypnotic agent for ESWL. (C) 1999 Elsevier, Paris.