Clinical investigation of bronchioloalveolar carcinoma: A retrospective analysis of 53 patients in a single institution

Background: Bronchioloalveolar carcinoma (BAL) has been reported to have un ique clinicopathological features. Patients and Methods; This retrospective study was performed using data base including 871 patients treated for pri mary lung cancer between 1981 and 1995. Results; The patients with BAC incl uded a larger proportion of female (P = 0.029) and smoked less (P = 0.002) than those with non-BAG. There was no difference in survival between surgic ally resected patients with BAC and those with non-BAG. Clinical Stage IV p atients with BAC had a better response to chemotherapy than did those with non-BAG. Survival in the former. group was better than that in the latter o n univariate analysis,: but the significance of this difference was not con firmed multivariate analysis. Conclusion; The patients with BAG included a larger proportion of females and smoked less than those with non-BAG treatm ent results for BAG was comparable to those for non-BAG.