Emergence in France of multiple clones of clinical Streptococcus pneumoniae isolates with high-level resistance to amoxicillin

Authors
Doit, C Loukil, C Fitoussi, F Geslin, P Bingen, E
Citation
C. Doit et al., Emergence in France of multiple clones of clinical Streptococcus pneumoniae isolates with high-level resistance to amoxicillin, ANTIM AG CH, 43(6), 1999, pp. 1480-1483
Citations number
18
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
6
Year of publication
1999
Pages
1480 - 1483
Database
ISI
SICI code
0066-4804(199906)43:6<1480:EIFOMC>2.0.ZU;2-3
Abstract
The genetic relatedness of French isolates of Streptococcus pneumoniae high ly resistant to amoxicillin (MIC, greater than or equal to 4 mu g/ml, equal to or exceeding those of penicillin) was investigated by molecular fingerp rinting. The results suggest that high-level resistance to amoxicillin has emerged within preexisting penicillin-resistant clones.