Activity of gatifloxacin compared to those of five other quinolones versusaerobic and anaerobic isolates from skin and soft tissue samples of human and animal bite wound infections
Ejc. Goldstein et al., Activity of gatifloxacin compared to those of five other quinolones versusaerobic and anaerobic isolates from skin and soft tissue samples of human and animal bite wound infections, ANTIM AG CH, 43(6), 1999, pp. 1475-1479
The activity of gatifloxacin against 308 aerobes and 112 anaerobes isolated
from bite wound infections was studied. Gatifloxacin was active at less th
an or equal to 0.016 mu g/ml against all 148 Pasteurella isolates (eight sp
ecies and three subspecies) tested and all other aerobes tested, including
Actinobacillus-Haemophilus spp., Eikenella corrodens, Neisseria weaveri, We
eksella zoohelcum, staphylococci, and streptococci. Fusobacteria were somet
imes resistant. Gatifloxacin MICs at which 90% of the isolates were inhibit
ed were 0.125 mu g/ml against Bacteroides tectum and Prevotella spp., 0.25
mu g/ml against Porphyromonas spp., and 0.5 mu g/ml against peptostreptococ
ci.