Why do viruses sometimes not pass through larger pores in track-etch filter
s? Increasing the salinity (0.8 to 160 mM Na+) decreased phi X174 and PRD1
passage through track-etch polycarbonate membranes (sodium dodecyl sulfate
coated but not polyvinylpyrrolidone coated) and PRD1 passage through polyes
ter membranes. Undiminished passage when 0.1% Tween 80 was added implied th
at nonionic virus adsorption occurred and indicated that high levels of sal
inity decreased virus passage by decreasing electrostatic repulsion that pr
evented adsorption.