G. Isacsson et D. Wasserman, Parasuicide and psychotropic medication: Clinical data and drugs used for overdose in 202 parasuicides, ARCH SUIC R, 5(2), 1999, pp. 113-123
We have earlier reported on medications used for overdose in 812 consecutiv
e parasuicides. Different studies have found some kind of depression in 30-
80% of parasuicides. Therefore, we then interpreted our finding that only 5
% used antidepressants for overdoses as a possible indicator of underprescr
ibing of these drugs in suicidal patients. In this study based on an extens
ive interview of 202 hospitalized parasuicides (69% psychiatric in-patients
), we found that women used antidepressants and anxiolytics relatively more
frequently for overdose (11% and 21%) than did men (3% and 8%), younger pe
rsons used more frequently analgesics (25%), and elderly more frequently hy
pnotics (75% in men above 75 years of age, and 57% in women above 75). Inte
restingly, those who took antidepressants in overdose reported lower suicid
e intent, while those who took anxiolytics reported more depressive symptom
s. It is concluded that depressive syndromes frequently includes symptoms o
f anxiety and that such patients should be treated with antidepressants and
not with anxiolytics alone.