A monoclonal antibody that recognizes the predicted tick-borne encephalitis virus E protein fusion sequence blocks fusion

Authors
Volkova, TD Vorovitch, MF Ivanov, VT Timofeev, AV Volpina, OM
Citation
Td. Volkova et al., A monoclonal antibody that recognizes the predicted tick-borne encephalitis virus E protein fusion sequence blocks fusion, ARCH VIROL, 144(5), 1999, pp. 1035-1039
Citations number
13
Categorie Soggetti
Microbiology
Journal title
ARCHIVES OF VIROLOGY
ISSN journal
03048608 → ACNP
Volume
144
Issue
5
Year of publication
1999
Pages
1035 - 1039
Database
ISI
SICI code
0304-8608(1999)144:5<1035:AMATRT>2.0.ZU;2-7
Abstract
The fusion motif of tick-borne encephalitis virus E protein has been predic ted to be located within its conserved region (98-120). Results are present ed to demonstrate that non-neutralizing monoclonal antibody which recognize s a synthetic peptide corresponding to residues 98-113 of the E protein seq uence can block the fusion of the virus particles with artificial membranes .