The activity and enantioselectivity of Candida rugosa lipase were investiga
ted in chiral solvents, (-)-, (+)- and racemic carvone, for the resolution
of 2-chloro-propionic acid with n-butanol via esterification. The activity
of the enzyme studied was about 50% higher in (-)-carvone than in (+)-carvo
ne, however the enantioselectivity was similar.