Isolation and characterization of new limonoid glycosides from Citrus unshiu peels

Authors
Sawabe, A Morita, M Kiso, T Kishine, H Ohtsubo, Y Minematsu, T Matsubara, Y Okamoto, T
Citation
A. Sawabe et al., Isolation and characterization of new limonoid glycosides from Citrus unshiu peels, CARBOHY RES, 315(1-2), 1999, pp. 142-147
Citations number
20
Categorie Soggetti
Agricultural Chemistry","Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
CARBOHYDRATE RESEARCH
ISSN journal
00086215 → ACNP
Volume
315
Issue
1-2
Year of publication
1999
Pages
142 - 147
Database
ISI
SICI code
0008-6215(19990131)315:1-2<142:IACONL>2.0.ZU;2-O
Abstract
Three limonoid glycosides were isolated from Citrus unshiu peels, and their structures were determined based on MS and NMR spectroscopic data as nomil inic acid 17-O-beta-D-glucopyranoside (1), methyl nomilinate 17-O-beta-D-gl ucopyranoside (2), and obacunone 17-O-beta-D-glucopyranoside (3). In partic ular, the location of the sugar moiety was clearly determined by the B/E co nstant linked scan FABMS method. No limonoid glycosides obtained here were found to have antitumor activity in NCI-H292 and EL-4 cell lines, (C) 1999 Elsevier Science Ltd. All rights reserved.