Biosynthesis of XR587 (streptopyrrole) in Streptomyces rimosus involves a novel carbon-to-nitrogen rearrangement of a proline-derived unit

Authors
Raggatt, ME Simpson, TJ Wrigley, SK
Citation
Me. Raggatt et al., Biosynthesis of XR587 (streptopyrrole) in Streptomyces rimosus involves a novel carbon-to-nitrogen rearrangement of a proline-derived unit, CHEM COMMUN, (11), 1999, pp. 1039-1040
Citations number
10
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
11
Year of publication
1999
Pages
1039 - 1040
Database
ISI
SICI code
1359-7345(19990607):11<1039:BOX(IS>2.0.ZU;2-7
Abstract
Results from incorporation studies with C-13-labelled acetate, propionate a nd proline establish a polyketide origin for the pyrrole-containing strepto mycete metabolite, XR587, and are in accord with the formation of an amide bond via an unprecedented rearrangement of a proline-derived starter unit.