Management of liver failure in a haemophilic patient co-infected with human immunodeficiency and hepatitis C viruses

We present a case of liver failure in a haemophilic patient coinfected with transfusion acquired human immunodeficiency (HIV) and hepatitis C (HCV) vi ruses. The case illustrates the interaction of multiple viruses with accele rated progression to end stage liver disease and ultimately death. We repor t the impact on the patient management of two liver biopsies, which diagnos ed an initial drug induced hepatitis and subsequently an atypical HCV relat ed hepatitis.