Environmentally acquired infections can be caused by animal contact, insect
vectors, or contaminated water. Obtaining an appropriately detailed histor
y is important in defining the differential diagnosis of possible infectiou
s diseases from the wilderness. Common clinical presentations include fever
with or without shock, lymphadenopathy or rash, altered mental status, dia
rrhea, and pneumonia. Diagnosis often depends on obtaining blood or body fl
uid for serology or culture. Antimicrobial treatment requires specific diag
nosis for optimal response.