Australia has a strong history of financing biotechnology ventures, with su
ccessful biotechnology companies including CSL, Biota, and AMRAD. These com
panies reflect a pool of extremely talented and productive Australian scien
tists, whose early primary research and later commercialisable research has
largely been funded by the Australian federal government. The Australian s
tock exchange is relatively receptive to biotechnology companies, although
at lower values than in international markets that provide public finance f
or more developed biotechnology ventures. The great financing challenge for
Australian biotechnology companies is bridging the gap between world-class
commercialisable primary science and listing on the public market. Recent
federal government initiatives have drawn significant resources to the earl
y-stage venture capital sector to address this problem in an attempt to mak
e available resources to seed and early-stage ventures with the discipline
of experienced venture capital investors. While this is a very positive ste
p, structural problems in the tax structure and lack of relevant skills in
management for early-stage biotechnology companies will continue to challen
ge Australian biotechnology ventures. Drug Dev. Res. 46:167-170, 1999. (C)
1999 Wiley-Liss, Inc.