Microtubule motors in spindle and chromosome motility

Many of the kinesin microtubule motor proteins discovered during the past 8 -9 years have roles in spindle assembly and function or chromosome movement during meiosis or mitosis. The discovery of kinesin motor proteins with a clear involvement in spindle and chromosome motility, together with recent evidence that cytoplasmic dynein plays a role in chromosome distribution, h as attracted great interest. The identification of microtubule motors that function in chromosome distribution represents a major advance in understan ding the forces that underlie chromosome and spindle movements during cell division.