Growth hormone treatment in a child with Williams-Beuren syndrome: a case report

Growth retardation is a consistent finding in Williams-Beuren syndrome. The cause of short stature in this syndrome is unknown. Endocrine studies have failed to reveal abnormalities in the growth hormone - insulin-like growth factor I axis. We report a boy with confirmed Williams-Beuren syndrome, wh o was found to have classical growth hormone deficiency and responded well to growth hormone therapy. Conclusion Although growth hormone deficiency is not likely to be a common cause of Short stature in Williams-Beuren syndrome, we nevertheless recomme nd evaluation of the growth hormone - insulin-like growth factor I axis in all cases.