Posturographic findings in patients with idiopathic cervical dystonia before and after local injections with botulinum toxin

Citation
C. Wober et al., Posturographic findings in patients with idiopathic cervical dystonia before and after local injections with botulinum toxin, EUR NEUROL, 41(4), 1999, pp. 194-200
Citations number
25
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
EUROPEAN NEUROLOGY
ISSN journal
00143022 → ACNP
Volume
41
Issue
4
Year of publication
1999
Pages
194 - 200
Database
ISI
SICI code
0014-3022(1999)41:4<194:PFIPWI>2.0.ZU;2-6
Abstract
In this posturographic study, whole-body postural control was impaired in m ore than 75% of patients with idiopathic cervical dystonia (ICD) before loc al injections with botulinum toxin type A (BTX-A) and the impairment was in dependent of the direction of the torticollis. Six weeks after therapy with BTX-A, the number of pathological posturographic parameters had decreased by almost 30%, and the improvement reached statistical significance for swa y path, sway area and anteroposterior sway during stance on foam with eyes closed. From a pathophysiological point of view, this improvement may be ex plained - at least in part- by a reduction of abnormal proprioceptive input from the neck. Accordingly, it seems possible that: neck proprioceptive in put plays a role in whole-body postural control in ICD patients, even thoug h previous studies suggested that the neck input is relatively ignored in t hese patients.