Detection of drug - tissue interactions using biosensors

Authors
Coon, DR Rechnitz, GA
Citation
Dr. Coon et Ga. Rechnitz, Detection of drug - tissue interactions using biosensors, FRESEN J AN, 364(1-2), 1999, pp. 175-178
Citations number
15
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
ISSN journal
09370633 → ACNP
Volume
364
Issue
1-2
Year of publication
1999
Pages
175 - 178
Database
ISI
SICI code
0937-0633(199905)364:1-2<175:DOD-TI>2.0.ZU;2-P
Abstract
Neuronal biosensors are employed to assess the effect of selected anti-HIV drugs on nerve tissue. Preliminary experimental results show that Zalcitabi ne and Didanosine produce interference in neural function and suggest a cor relation with clinically observed neuropathy. Zidovudine (AZT) produced no observable effect.