Gastro-oesophageal reflux: the disease of the millennium

Authors
Navaratnam, RM Winslet, MC
Citation
Rm. Navaratnam et Mc. Winslet, Gastro-oesophageal reflux: the disease of the millennium, HOSP MED, 59(8), 1998, pp. 646-649
Citations number
22
Categorie Soggetti
General & Internal Medicine
Journal title
HOSPITAL MEDICINE
ISSN journal
14623935 → ACNP
Volume
59
Issue
8
Year of publication
1998
Pages
646 - 649
Database
ISI
SICI code
1462-3935(199808)59:8<646:GRTDOT>2.0.ZU;2-Z
Abstract
Gastro-oesophageal reflux disease (GORD) is attributable primarily to acid and bile reflux through the lower oesophageal sphincter. Bile reflux has be en implicated in severe oesophagitis, Barrett's oesophagus and oesophageal adenocarcinoma. Developments in evaluating and managing GORD and Barrett's are discussed, with their aetiological role in junctional gastro-oesophagea l malignancies.