We have determined the nature and extent of variation at 4 STR loci (CSF1P0
, TPOX, TH01, VWA) in 8 caste and tribal population groups of eastern and n
orthern India, Large differences in allele frequencies among the groups wer
e found. Average heterozygosities in all populations were high (approximate
to 80%). The overall extent of gene differentiation among the 8 groups was
high (G(ST) = 0.04). The nature of genomic affinities based on these 4 STR
loci does not completely agree with our earlier finding based on classical
genetic markers that geographic proximity of habitat has a greater influen
ce on genetic similarity between populations than sociocultural proximity d
oes.