Variation at 4 short tandem repeat loci in 8 population groups of India

Citation
N. Mukherjee et al., Variation at 4 short tandem repeat loci in 8 population groups of India, HUMAN BIOL, 71(3), 1999, pp. 439-446
Citations number
11
Categorie Soggetti
Medical Research General Topics
Journal title
HUMAN BIOLOGY
ISSN journal
00187143 → ACNP
Volume
71
Issue
3
Year of publication
1999
Pages
439 - 446
Database
ISI
SICI code
0018-7143(199906)71:3<439:VA4STR>2.0.ZU;2-M
Abstract
We have determined the nature and extent of variation at 4 STR loci (CSF1P0 , TPOX, TH01, VWA) in 8 caste and tribal population groups of eastern and n orthern India, Large differences in allele frequencies among the groups wer e found. Average heterozygosities in all populations were high (approximate to 80%). The overall extent of gene differentiation among the 8 groups was high (G(ST) = 0.04). The nature of genomic affinities based on these 4 STR loci does not completely agree with our earlier finding based on classical genetic markers that geographic proximity of habitat has a greater influen ce on genetic similarity between populations than sociocultural proximity d oes.