Purpose: Changes in refractive error have been reported after strabismus su
rgery. The influence of extraocular muscle tension on corneal topography is
thought to be an important mechanism contributing to this alteration. This
study investigates topographic changes after strabismus surgery in human b
eings. Methods: The corneal topography of 63 eyes of 43 patients who underw
ent either strabismus or optic nerve sheath fenestration (ONSF) surgery was
measured before and after operation. The ONSF surgery involved removing an
d reattaching the medial rectus muscle, thus acting as a control for the st
rabismus procedures. Corneal power was measured centrally and at 1.5 and 3.
0 mm in 8 meridians. Analysis of variance was performed to compare the diff
erence in preoperative and postoperative corneal power for all procedures a
nd comparing recessions, resections, combined recession and resection, and
ONSF as grouped procedures. Results: All groups showed a significant change
in preoperative to postoperative corneal power (P<.01). A significant chan
ge was seen between all grouped procedures except when the resection was co
mpared with ONSF and compared with recession. Conclusions: Change in the te
nsion of 1 muscle does not produce a change in the adjacent quadrant as muc
h as it produces a significant change in the entire corneal surface, which
illustrates the interaction and interdependence all corneal positions have
with respect to each other.