Components of the ether-insoluble resin glycoside fraction from the seed of Cuscuta australis

An ether-insoluble resin glycoside fraction was obtained from the seeds of Cuscuta australis, identification and characterization of alkaline hydrolys is products by means of GC, FABMS, and H-1, C-13, and 2D NMR revealed the m aterial to be composed of three new glycosidic acids, cuscutic acids A(1)-A (3) (1-3); triglycosides with (11S)-jalapinolic or (11S)-convolvulinolic ac id as the aglycon; and acetic, isobutyric, (2S)-2-methylbutyric, tiglic, an d (2R,3R)-nilic acids. The resin glycoside is considered to be a complex mi xture of glycosidic ester-type oligomers (up to heptamers) with a core cons isting of a number of the above cuscutic acids each acylated with one or tw o carboxylic acid moieties.