Two bioactive pentacyclic triterpene esters from the root bark of Hibiscussyriacus

Authors
Yun, BS Ryoo, IJ Lee, IK Park, KH Choung, DH Han, KH Yoo, ID
Citation
Bs. Yun et al., Two bioactive pentacyclic triterpene esters from the root bark of Hibiscussyriacus, J NAT PROD, 62(5), 1999, pp. 764-766
Citations number
10
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
5
Year of publication
1999
Pages
764 - 766
Database
ISI
SICI code
0163-3864(199905)62:5<764:TBPTEF>2.0.ZU;2-C
Abstract
Two new triterpene caffeates have been isolated from the root bark of Hibis cus syriacus. Their structures were established through various spectral st udies as 3 beta,23,28-trihydroxy-12-oleanene 23-caffeate (1) and 3 beta,23, 28-trihydroxy-12-oleanene 3 beta-caffeate (2). Compounds 1 and 2 showed lip id peroxidation inhibitory activity and significant cytotoxicity against a panel of human cancer cell lines.