Incidence of and preoperative predictors for postoperative delirium were st
udied in 296 patients (age 26-83 years, mean age 63 years) undergoing elect
ive cardiac surgery. Delirium occurred in 40 (13.5%) patients. Predictors i
ncluded old age, low level of albumin, poor physical condition, use of nife
dipine, and a high ratio of the amino acids phenylalanine to the sum of iso
leucine, leucine, valine, tyrosine, and tryptophan. These findings suggest
that preoperative physical condition and amino acid disturbances may be rel
ated to delirium after cardiac surgery in the elderly. (C) 1999 Elsevier Sc
ience Inc.