Successful treatment of severe muscle necrosis with intravenous immunoglobulin

Intravenous immunoglobulin (IVIG) is an effective treatment for a range of conditions believed to have an autoimmune basis, including inflammatory mus cle disease. We describe a patient with muscle disease characterized by sev ere necrosis without clinical or biopsy evidence of inflammation or vasculi tis, who responded to treatment with IVIG.