The value of derangements of left ventricular systolic and diastolic functions for prognostication of the course of ischemic heart disease after extracardiac surgery in cancer patients

For determination of risk of exacerbations of ischemic heart disease after extracardiac surgery 69 patients with stable effort II-III functional class angina aged 44-79 (mean 65+/-0,89) years were examined by electro-, echo- and doppler echocardiography at rest and after hyperventilation, exercise a nd cold presser tests. Factorial regression analysis showed that for estima tion of operative risk it was expedient to determine index of local left ve ntricular contractility disturbances and to study reaction of left ventricu lar diastolic function to exercise and cord. High risk patients were charac terized by restrictive type of reaction of diastolic function to exercise a nd by augmentation of the type with preponderance of peak atrial filling du ring cold presser test. Most informative parameters of transmitral flow wer e M-1/M-2, deceleration time of early filling and normalized velocity of bl ood flow.