The aim of our experimental study was to gain informations and data on the
driving ability of patients undergoing a methadone substitution programme a
s well as to explore the influence of an HIV infection. 28 patients, five o
f them HIV-positive, were compared to a control group equal in age, sex and
education. For the traffic relevant tests the methadone patients showed si
gnificantly reduced performance. Six of the methadone patients passed the t
ests in a way regarded to have sufficient driving skills. We were unable to
prove an influence of HIV infection on driving skills when lacking relevan
t somatic and neuropsychiatric symptoms. There was no significant correlati
on between the test results and patients age or dose of medication. We conc
lude that in general methadone substitution does not implicate driving inab
ility although the majority of our patients showed some reduction of their
psychomotoric skills.