S. Woyke et al., ATYPICAL LIPOMA AS A POTENTIAL PITFALL IN THE CYTODIAGNOSIS OF SUBCUTANEOUS TUMORS - A REPORT OF 2 CASES, Acta cytologica, 41(3), 1997, pp. 897-902
BACKGROUND: If well-differentiated liposarcomas of lipomalike type occ
ur in the subcutis, they behave as benign neoplasms. For these tumors
the term atypical lipoma was introduced in 1975. Fine needle aspiratio
n (FNA) findings in these tumors may raise a false impression of malig
nancy. CASES: Females aged 34 and 48 years presented with well-defined
subcutaneous nodules in the left supraclavicular region and on top of
the head, respectively FNA showed fragments of mature fat tissue and
numerous dispersed, large, hyperchromatic, often bizarre nuclei. Lipom
a with atypical cells was diagnosed cytologically in one case and atyp
ical lipoma in the other. Histologically both cases were evaluated as
atypical lipoma. CONCLUSION: A correct cytologic diagnosis atypical li
poma can be established if cytomorphologic features are coupled with c
linical data.