Tubulointerstitial nephritis and uveitis in association with Epstein-Barr virus infection

The case of a 13.5-year-old girl with acute tubulointerstitial nephritis an d uveitis (TINU syndrome) is presented. The etiology of this rare syndrome, which in most cases involves female adolescents and usually regresses spon taneously, is still unknown. An infection-triggered pathological immune rea ction has been considered to play a role in the pathogenesis of this disord er. Here we report for the first time the association of TINU syndrome and Epstein-Barr virus infection.