Studies on the microbial transformation of the sesquiterpene endoperoxide a
rtemisitene have revealed that artemisitene was metabolized by Aspergillus
niger (NRRL 599) to yield 11-epi-artemisinin,9 beta-hydroxydeoxy-11-epi-art
emisinin and 9 beta-hydroxy-11-epi-artemisinnin. These metabolites were cha
racterized on the basis of their spectral data. (C) 1999 Elsevier Science L
td. All rights reserved.