Synthesis of sucrose derivatives modified at the terminal carbon atoms

The methodology for the preparation of various derivatives of sucrose modif ied at Cl', CG, and C6'-positions is presented. 6-Amino-, 6'-amino-, and 6, 6'-diamino-penta-O-benzylsucroses (16, 17 and 18 respectively), as well as appropriate uronic acids (characterized as methyl esters: 19-22), have been obtained from 2,3,4,3'4'-penta-O-benzyl-sucrose (1). The usefulness of thi s approach was exemplified by the preparation of 1'-O-benzyloxymethyl-6-deo xy-6-C-(2-furyl)-2,3,4,3'4'-penta-O-benzylsucrose (26).