Objective: Although a strong association between violence and psychopathy h
as been demonstrated in nonpsychotic forensic populations, the relationship
between psychopathy and violence among patients with schizophrenia has not
been thoroughly explored. Patients with and without a history of persisten
t violent behavior were compared for comorbidity of psychopathy and schizop
hrenia or schizoaffective disorder. Methods: Violent and nonviolent patient
s were identified through reviews of hospital charts and records of arrests
and convictions. The Psychopathy Checklist: Screening Version was administ
ered to 51 patients, 26 violent patients and 25 matched nonviolent patients
. Analysis of variance was used as the principal statistical method for com
paring violent and nonviolent groups. Results: Mean psychopathy scores were
higher for violent patients than nonviolent patients. Five of the violent
patients (19 percent) had scores exceeding the cutoff for psychopathy, and
13 (50 percent) scored in the possible psychopathic range. All of the nonvi
olent patients scored below the cutoff for possible psychopathy Higher psyc
hopathy scores were associated with earlier age of onset of illness and mor
e arrests for both violent and nonviolent offenses. Conclusions: The comorb
idity of schizophrenia and psychopathy was found to be higher among violent
patients than among nonviolent patients. Violent patients with schizophren
ia who score high on measures of psychopathy may have a personality disorde
r that precedes the emergence of psychotic symptoms, or they may constitute
a previously unclassified subtype of schizophrenia, characterized by early
symptoms of conduct disorder symptoms and persistent violent behavior.