A BIOACTIVE SECO-ROSANE DITERPENOID FROM VELLOZIA-CANDIDA

Authors
VALENTE LMM GUNATILAKA AAL KINGSTON DGI PATITUCCI ML PINTO AC
Citation
Lmm. Valente et al., A BIOACTIVE SECO-ROSANE DITERPENOID FROM VELLOZIA-CANDIDA, Journal of natural products, 60(5), 1997, pp. 478-481
Citations number
11
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
60
Issue
5
Year of publication
1997
Pages
478 - 481
Database
ISI
SICI code
0163-3864(1997)60:5<478:ABSDFV>2.0.ZU;2-9
Abstract
Bioassay-directed fractionation of the bioactive alcoholic extracts of Vellozia candida yielded a new 6,7-seco-rosane diterpenoid, candidala ctone (1), which showed moderate toxicity toward DNA repair-deficient mutants of Saccharomyces cerevisiae. Another new but inactive rosane d iterpenoid, candidenodiol (3), was also obtained.